BOULDER -- Colorado's Lawrence Vickers compiled 168 total yards, but it was Oklahoma State's Vernand Morency who stole the show as the No. 22 Cowboys downed the Buffaloes 42-14 Saturday at Folsom Field.

Morency ran for 165 yards and two touchdowns as OSU (5-0, 2-0 Big 12) established its powerful running game early. Morency scored on a 58-yard touchdown run on the Cowboy's third play and added a 6-yard touchdown run in the second quarter, eclipsing 100 yards for the seventh straight regular season game.

The dominance up front opened up Oklahoma State's passing game.

OSU quarterback Donovan Woods bounced back from a bad interception in the first quarter -- just the second turnover in five games for the Cowboys -- with 58-yard touchdown pass to Prentis Elliott on the final play of the first half.

Woods also had a 20-yard touchdown pass to Luke Frazier to put the Cowboys up 28-0 in the third quarter, and added a 53-yarder in the fourth when no one covered D'Juan Woods on a third down.

Vickers had 168 total yards -- 72 rushing, 96 receiving -- and scored on a 6-yard touchdown run early in the fourth quarter. He just didn't get much help.

Colorado (3-2, 0-2) finished with 445 total yards, but failed on four other trips inside Oklahoma State's 30. The Buffaloes also had two key mistakes in the second quarter that kept the game from staying close.

The first came midway through the second quarter, when freshman Hugh Charles ran into punt returner Stephone Robinson, who was trying to make a fair catch. The ball hit Charles' foot after the two collided and Oklahoma State's Vernon Grant recovered at Colorado's 11, setting up Morency's 5-yard touchdown run.

The next mistake came when the Buffaloes were caught offguard at a time when they shouldn't have been surprised.

At its 42 with the final seconds ticking off, Oklahoma State came out in a normal formation instead of loading a bunch of receivers on one side for a final desperation play. Colorado took the bait and left Oklahoma State's Prentiss Elliott with one-on-one coverage up the middle.

Big mistake.

Elliott slipped behind Lorenzo Sims on a post pattern, caught the ball at the 5-yard line when the Colorado defender fell, then staggered into the end zone for a 58-yard touchdown as time expired to put Oklahoma State up 21-0.

Colorado's offense didn't help matters.

Mason Crosby hooked a 52-yard field goal wide left on the Buffaloes' first drive and two more drives ended inside Oklahoma State's 20 on failed fourth-down attempts. Colorado also reached the 10 on its first drive of the third quarter, only to have that drive end when Paul Duren dived in front of Joe Klopfenstein to intercept James Cox's pass at the 5.

Duren also returned an interception 34 yards for a touchdown late in the fourth quarter.

Cox was 15-for-21 for 175 yards and two touchdowns after replacing Joel Klatt in the second half. Klatt sat out with a stiff neck after being hit in the head late in the second quarter.